Couzin's "As Gelsinger Case Ends,Gene Therapy Suffers Another Blow" 2005

From Biol557

[edit] Introduction

• 18 year old (Gelsinger) died in a gene therapy experiment
• In another trial for gene therapy a child developed leukemia from severe combined immunodeficiency (X-SCID)
  • However 17 children have been succesfuuly treated for SCID using gene therapy
  • Speculated that cells with the oncogene insertion proliferated more readily in young children (causing leukemia)