Kluver-Bucy syndrome
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[[Category:Neuropsychological syndromes]] | [[Category:Neuropsychological syndromes]] | ||
| - | '''Kluver-Bucy syndrome''' is a neurobehavioral disorder that occurs when there is damage to the | + | '''Kluver-Bucy syndrome''' is a rare neurobehavioral disorder that occurs when there is bilateral damage to the medial temporal lobes in the brain. The syndrome is named for Heinrich Kluver and Paul Bucy, who attempted to determine its function by removing the temporal lobe bilaterally in rhesus monkeys. '''Kluver-Bucy syndrome''' can be characterized as one having oral tendencies (by putting things in their mouth), placidity (an absence of emotional response - being serene), and increased sexual activity. However, there was discovered different effects in monkeys and humans. |
== In Rhesus Monkeys == | == In Rhesus Monkeys == | ||
''Symptoms'' | ''Symptoms'' | ||
| - | + | * Oral tendencies: They would have a desire to explore everything examine their world with their mouths instead of their eyes | |
| - | + | * Hypersexualism: Their overt sexual behavior increased dramatically and the monkeys indulged in indiscriminate sexual behavior including masturbation, heterosexual and homosexual acts. | |
| - | + | * Emotional changes: The monkeys became less expressive in their face and vocalizations. There is also a loss of normal fear and anger responses. For example, even after being attacked by a snake, the monkey would willingly approach it again; these changes are connected to any lesion of the [[amygdala | |
| - | + | * [[Visual agnosia]]: Though the monkeys could see, they were unable to recognize even previously familiar objects, or their use | |
== In Humans == | == In Humans == | ||
| Line 20: | Line 20: | ||
==External links== | ==External links== | ||
* [http://www.ninds.nih.gov/disorders/kluver_bucy/kluver_bucy.htm The National Institute of Neurological Disorders and Stroke - Kluver-Bucy Syndrome] | * [http://www.ninds.nih.gov/disorders/kluver_bucy/kluver_bucy.htm The National Institute of Neurological Disorders and Stroke - Kluver-Bucy Syndrome] | ||
| - | *[http://neuro.psychiatryonline.org/cgi/content/full/11/1/116 Anatomic Basis of | + | *[http://neuro.psychiatryonline.org/cgi/content/full/11/1/116 Anatomic Basis of Kluver-Bucy Syndrome] |
*[http://cogprints.org/2872/ Monkeys With Amygdala Lesions] | *[http://cogprints.org/2872/ Monkeys With Amygdala Lesions] | ||
*[http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=3;spage=369;epage=371;aulast=Jha Six distinct case studies of KBS in India] | *[http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=3;spage=369;epage=371;aulast=Jha Six distinct case studies of KBS in India] | ||
Current revision as of 16:31, 27 April 2008
Kluver-Bucy syndrome is a rare neurobehavioral disorder that occurs when there is bilateral damage to the medial temporal lobes in the brain. The syndrome is named for Heinrich Kluver and Paul Bucy, who attempted to determine its function by removing the temporal lobe bilaterally in rhesus monkeys. Kluver-Bucy syndrome can be characterized as one having oral tendencies (by putting things in their mouth), placidity (an absence of emotional response - being serene), and increased sexual activity. However, there was discovered different effects in monkeys and humans.
In Rhesus Monkeys
Symptoms
- Oral tendencies: They would have a desire to explore everything examine their world with their mouths instead of their eyes
- Hypersexualism: Their overt sexual behavior increased dramatically and the monkeys indulged in indiscriminate sexual behavior including masturbation, heterosexual and homosexual acts.
- Emotional changes: The monkeys became less expressive in their face and vocalizations. There is also a loss of normal fear and anger responses. For example, even after being attacked by a snake, the monkey would willingly approach it again; these changes are connected to any lesion of the [[amygdala
- Visual agnosia: Though the monkeys could see, they were unable to recognize even previously familiar objects, or their use
In Humans
People with a bilateral lesion in their temporal lobes show similar behaviors to the monkeys such as an oral tendency to explore, hypersexuality, and flattened emotions. In addition, other behaviors may include tactile exploratory behavior (socially inappropriate touching), bulimia, memory disorders, visual agnosia or prosopagnosia.
Aside from accidental damage, extensive bilateral temporal damage can arise from herpes, encephalitis, cardiovascular disease, and dementias of degenerative (Alzheimer's Disease) or post-traumatic origins. In general, the syndrome rarely develops in humans.
