Crystal's "Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis" 1994
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===Introduction=== | ===Introduction=== | ||
| + | * CF is a common lethal hereditary disorder caused by a mutation on CFTR on chromosome 7 | ||
| + | * The disorder is characterized by airway and gastrointestinal disease, the lung manifestations dominate | ||
| + | * The pathogenesis is clearly linked to the lack of CFTR in the respiratory epithelia | ||
| + | * Symptoms in first decade: | ||
| + | ** Thick mucus, colonization with infectious bacteria, and chronic airway inflammation | ||
| + | * One approach to prevent respiratory manifestations of CFTR is gene therapy (talked about in abstract) | ||
| + | * Gene therapy must be carried out in vivo, cannot be done ex vitro | ||
Revision as of 18:36, 3 March 2010
Abstract
- Just put an asterisk as the first character to make a bullet point.
- Put two asterices to make a sub point.
- Put three single quote marks around text you want to be bold, perhaps for new terminology.
- Put two single quotes around things that should be italicized.
Introduction
- CF is a common lethal hereditary disorder caused by a mutation on CFTR on chromosome 7
- The disorder is characterized by airway and gastrointestinal disease, the lung manifestations dominate
- The pathogenesis is clearly linked to the lack of CFTR in the respiratory epithelia
- Symptoms in first decade:
- Thick mucus, colonization with infectious bacteria, and chronic airway inflammation
- One approach to prevent respiratory manifestations of CFTR is gene therapy (talked about in abstract)
- Gene therapy must be carried out in vivo, cannot be done ex vitro
