Tie her up.
From Create Your Own Story
You grab anything you can. Electrical cords, the string from the blinds, a couple of old shirts, and you tie the girl's hands and feets so tight that she'll be lucky if you can ever get them undone. Provided she ever gets well again. Slumping onto the couch, you pick up the wine bottle and have yourself a drink. Or two. Or Three. It's been that kind of day.
You sit and listen to the distant gunfire. It's sporadic, but there's more than zero gunfire, which is what you're used to. Every now and then you hear an explosion, but eventually the thunder over head blends in. As the rain spatters in sideways against your apartment windows, you wonder what the hell is happening. Is it some sort of virus causing everyone to go crazy? Is that it. Like...that one movie with the running zombies you saw? Except they weren't really zombies? Or something?
Just then, there's a growl from the tethered woman, and she turns on the floor to eyeball you. Yet, she seems to be staring through you, unable to recognize the face she saw just ten minutes beforehand. Her teeth gnash, and she struggles to tear free of her bondage. You stand up and raise the wine-bottle. "Don't make me hit you. Lie still."
Still, the woman struggles. You consider giving her another thwomp. She seems to be tied up well enough. Maybe just a gag to keep her from screaming or drawing attention.
You don't hesitate. There's been too much violence and weirdness already. When she's in arm's reach, you lash out with a punch that sends her crumpled body to the floor. When she lands, she goes face first, and one of the two impacts has broken her nose. Blood spatters across the floor and speckles the tips of your shoes.
"Jesus," you say quietly. "What the fuck is going on?"
You aren't sure how long she'll be out. You're not a fighter. This isn't your bag. You have to do something quick.